Every time we travel for a vacation or just an out of town get away, we always make sure that our baby's car seat is safe for long drives. If we travel by plane, we always have her car seat with us just to make sure that she has something to use when we arrived at our destination. We are confident as well that the car seat she is using is safe. You have to plan in advance and anticipate things your baby might need for you to be able to enjoy your vacation without so much fuss.
If you are worried that the hotel you might be staying is baby friendly or not, you can check out BabySafe Travel.com. They indicated all the hotels with their amenities, and tips on Hotel Safety and Baby Proofing Techniques. They even give travel tips to parents if they have a baby or a toddler. I love their tips on Recommended Baby Gear for Happy Travelling. So much information in this site that would help you travel with baby safely and full of fun!
They even have baby products from bath gear, diaper bags, baby carriers to strollers. I love their feeding time products too. Very unique!